Qing gan zhi ling tang biography
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Si-Wei-Qing-Gan-Tang Improves Non-Alcoholic Steatohepatitis by Modulating the Nuclear Factor-κB Signal Pathway and Autophagy in Methionine and Choline Deficient Diet-Fed Rats
Introduction
Non-alcoholic fatty liver disease (NAFLD) is a metabolic liver disease characterized by excess lipid deposition in hepatocytes, and its disease spectrum includes non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma (HCC) (Ullah et al., ). The current global incidence of NAFLD is about %, and approximately 59% of the NALFD patients with structural liver biopsy have progressed to NASH (Younossi et al., ). Remarkably, NASH has become the second most common cause for liver transplantation, while NAFLD and NASH are the second major cause of HCC (Fazel et al., ).
The pathogenesis of NASH is not fully understood. Current theories suggest that inflammation is an important factor in the development of simple steatosis to NASH (Pierantonelli and Svegliati-Baroni, ). Infl
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Ding Ling
Chinese writer (–)
For the ancient Siberian people, see Dingling.
In this Chinese name, the family name is Ding.
Ding Ling | |
|---|---|
| Born | Jiang Bingzhi ()12 October Linli, Hunan, China |
| Died | 4 March () (aged&#;81) Beijing, China |
| Occupation | Writer |
| Language | Chinese |
| Notable works | Miss Sophia's Diary The Sun Shines over the Sanggan River |
| Spouse | Hu Yepin Feng Da Chen Ming |
| Children | 2 |
Ding Ling (Chinese: 丁玲; pinyin: Dīng Líng; October 12, – March 4, ), formerly romanized as Ting Ling, was the pen name of Jiang Bingzhi (simplified Chinese: 蒋冰之; traditional Chinese: 蔣冰之; pinyin: Jiǎng Bīngzhī), also known as Bin Zhi (彬芷 Bīn Zhǐ), one of the most celebrated Chinese women authors of the 20th century. She is known for her feminist and socialist realist literature.[1]
Ding was active in leftist literary circles connected to the Chinese Communist Party and was imprisoned by the Chinese Nationalist Par
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Abstract
Si-Wei-Qing-Gan-Tang (SWQGT) fryst vatten a kinesisk medicine formula that fryst vatten widely used as a folk remedy of herbal tea for the treatment of chronic hepatitis, like non-alcoholic steatohepatitis (NASH), around Ganzhou City (Jiangxi province, China). However, the underlying mechanisms of this formula against NASH are still unknown. This study aimed to explore the effect and mechanisms of SWQGT against NASH. A network pharmacology approach was used to predict the potential mechanisms of SWQGT against NASH. Then a rat model of NASH established by feeding the methionine and choline deficient (MCD) diet was used to verify the effect and mechanisms of SWQGT on NASH in vivo. SWQGT (1 g/kg/d and 3 g/kg/d) were given bygd intragastric ledning. Body vikt, liver vikt, serum biochemical indicators, liver triglyceride and total kolesterol were all measured. Tumor necrosis factor-α (TNF-α), Interleukin (IL)-1β, IL-6 levels in the livers were evaluated using ELISA. Hematoxylin and eosi