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  • Técnico comercial Asturias.
  • Mufioz-Sobrino, C., Ramil-Rego, P. & Rodriguez Guitian,.
  • The case study clearly shows that the retrospective analysis of HRMS/MS data can improve the current knowledge on exposure and the related risks to chemicals.
  • Abstract

    A method for detecting the organophosphorus pesticides residue and aflatoxins in China herbal tea has been developed by UPLC-MS/MS coupled with vortex-assisted dispersive liquid-liquid microextraction (DLLME). The extraction conditions for vortex-assisted DLLME extraction were optimized using single-factor experiments and response surface design. The optimum conditions for the experiment were the pH 5.1, 347 µL of chloroform (extraction solvent) and 1614 µL of acetonitrile (dispersive solvent). Under the optimum conditions, the targets were good linearity in the range of 0.1 µg/L–25 µg/L and the correlation coefficient above 0.9998. The mean recoveries of all analytes were in the ranged from 70.06%–115.65% with RSDs below 8.54%. The detection limits were in the range of 0.001 µg/L–0.01µg/L. The proposed method is a fast and effective sample preparation with good enrichment and extraction efficiency, which can simultaneously detect pesticides and aflatoxins in China herbal

    World Bank Listing of Ineligible Firms and Individuals

    Table 2: Other Sanctions 

    Name of Firm & Address

    Date of Imposition of Sanction

    Sanction Imposed

    Grounds

    OAO Armada *12

    Ongoing

    Letter of reprimand

    Sanctions Procedures, Section 9.04(a)

    PT. Bumirejo *13

    Ongoing

    Letter of reprimand‚

    January 1999 Procurement Guidelines, para. 1.15(a)(ii)

    NIPPON KOEI CO., LTD. *58

    5-4, KOJIMACHI, CHIYODA-KU, TOKYO, 102-8539, JAPAN
    June 22, 2023 – June 21, 2025Conditional Non-debarmentFraudulent Practices
    NIPPON KOEI VIETNAM INTERNATIONAL CO., LTD *58

    10TH FLOOR, TOWER A, HANDI-RESCO BUILDING, 521 KIM MA, NGOC KHANH WARD, BA DINH DISTRICT, HANOI, VIETNAM
    June 22, 2023  – June 21, 2025Conditional Non-debarmentFraudulent Practices

    TPF GETINSA EUROESTUDIOS S.L. *59

    Ramón de Aguinaga, 8

    Madrid, 28028

    Spain

    Feberuary 29, 2024 - November 28, 2027Conditional Non-debarmentCor
  • ramil rodriguez biography sample
  • Generation of human immortalized chondrocytes from osteoarthritic and healthy cartilage

    Article focus

    • Primary human articular chondrocytes tend to senesce and lose their phenotype when cultured in vitro.

    • Available chondrocyte fängelse lines that have been generated from cartilage sources different from synovial joints have limited use for osteoarthritis (OA) research.

    • For these reasons, we aimed to generate immortalized chondrocyte fängelse lines derived from the articular cartilage of patients with and without OA.

    Key messages

    • Transduction of articular chondrocytes with SV40 large T antigen and telomerase reverse transcriptase allows them to overcome senescence in vitro.

    • Immortalized articular chondrocytes upregulate inflammatorisk mediators interleukin (IL)-6, IL-8, and cyclooxygenase-2 when stimulated with IL-1β in a similar way to primary articular chondrocytes.

    • However, immortalized articular chondrocytes were unable to form cartilage-like tissue beneath th